Recurrent pregnancy loss (RPL) afflicts 2-4% of reproductive-aged women and is defined as two or more pregnancy losses.
A thorough evaluation is required to diagnose the cause of RPL. Causes include:
- immune factors
- anatomic factors (e.g. abnormalities in the anatomy of the uterus)
- genetic factors, in a woman, her male partner, or the fetus
- endocrine factors (e.g. thyroid disease, diabetes),
- thrombophilia factors (i.e. blood clotting disorders),
- environmental factors, which may be found at work, at home or following certain medical procedures
- lifestyle issues (e.g. tobacco use or heavy alcohol use)
Following such an evaluation, treatment options will be discussed aimed at helping couples avoid another pregnancy loss.